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Transthyretin Promotes Axon Growth via Regulation of Microtubule Dynamics and Tubulin Acetylation
Transthyretin (TTR), a plasma and cerebrospinal fluid protein, increases axon growth and organelle transport in sensory neurons. While neurons extend their axons, the microtubule (MT) cytoskeleton is crucial for the segregation of functional compartments and axonal outgrowth. Herein, we investigated...
Autores principales: | Eira, Jessica, Magalhães, Joana, Macedo, Nídia, Pero, Maria Elena, Misgeld, Thomas, Sousa, Mónica M., Bartolini, Francesca, Liz, Márcia A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606651/ https://www.ncbi.nlm.nih.gov/pubmed/34820375 http://dx.doi.org/10.3389/fcell.2021.747699 |
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