Complement Factor H-Related 3 Enhanced Inflammation and Complement Activation in Human RPE Cells

Complement Factor H-Related 3 (FHR-3) is a major regulator of the complement system, which is associated with different diseases, such as age-related macular degeneration (AMD). However, the non-canonical local, cellular functions of FHR-3 remained poorly understood. Here, we report that FHR-3 bound...

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Detalles Bibliográficos
Autores principales: Schäfer, Nicole, Rasras, Anas, Ormenisan, Delia M., Amslinger, Sabine, Enzmann, Volker, Jägle, Herbert, Pauly, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606654/
https://www.ncbi.nlm.nih.gov/pubmed/34819935
http://dx.doi.org/10.3389/fimmu.2021.769242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606654/
https://www.ncbi.nlm.nih.gov/pubmed/34819935
http://dx.doi.org/10.3389/fimmu.2021.769242

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