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Complement Factor H-Related 3 Enhanced Inflammation and Complement Activation in Human RPE Cells
Complement Factor H-Related 3 (FHR-3) is a major regulator of the complement system, which is associated with different diseases, such as age-related macular degeneration (AMD). However, the non-canonical local, cellular functions of FHR-3 remained poorly understood. Here, we report that FHR-3 bound...
Autores principales: | Schäfer, Nicole, Rasras, Anas, Ormenisan, Delia M., Amslinger, Sabine, Enzmann, Volker, Jägle, Herbert, Pauly, Diana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606654/ https://www.ncbi.nlm.nih.gov/pubmed/34819935 http://dx.doi.org/10.3389/fimmu.2021.769242 |
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