Baicalin Enhanced Oral Bioavailability of Sorafenib in Rats by Inducing Intestine Absorption

Background: Sorafenib (SOR) is an oral, potent, selective, irreversible epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) used as the first-line therapy for advanced hepatocellular carcinoma (HCC). Baicalin (BG) is used as adjuvant therapy for hepatitis, which accounts for the le...

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Detalles Bibliográficos
Autores principales: Wei, Jingyao, Liu, Ruijuan, Zhang, Jiali, Liu, Shuaibing, Yan, Dan, Wen, Xueqian, Tian, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606670/
https://www.ncbi.nlm.nih.gov/pubmed/34819863
http://dx.doi.org/10.3389/fphar.2021.761763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606670/
https://www.ncbi.nlm.nih.gov/pubmed/34819863
http://dx.doi.org/10.3389/fphar.2021.761763

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