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Cardiomyocyte protein O-GlcNAcylation is regulated by GFAT1 not GFAT2
In response to cardiac injury, increased activity of the hexosamine biosynthesis pathway (HBP) is linked with cytoprotective as well as adverse effects depending on the type and duration of injury. Glutamine-fructose amidotransferase (GFAT; gene name gfpt) is the rate-limiting enzyme that controls f...
Autores principales: | A Nabeebaccus, Adam, Verma, Sharwari, Zoccarato, Anna, Emanuelli, Giulia, Santos, Celio XC., Streckfuss-Bömeke, Katrin, Shah, Ajay M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606754/ https://www.ncbi.nlm.nih.gov/pubmed/34735873 http://dx.doi.org/10.1016/j.bbrc.2021.10.056 |
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