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An In Silica Model for RPE Loss Patterns in Choroideremia

PURPOSE: To use empirical data to develop a model of cell loss in choroideremia that predicts the known exponential rate of RPE loss and central, scalloped preservation pattern seen in this disease. METHODS: A computational model of RPE loss was created in Python 3.7, which constructed an array of R...

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Detalles Bibliográficos
Autores principales: Young, Benjamin K., Shen, Liangbo L., Del Priore, Lucian V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606796/
https://www.ncbi.nlm.nih.gov/pubmed/34779822
http://dx.doi.org/10.1167/iovs.62.14.10