LncRNA NEAT1 Recruits SFPQ to Regulate MITF Splicing and Control RPE Cell Proliferation

PURPOSE: Retinal pigment epithelium (RPE) cell proliferation is precisely regulated to maintain retinal homoeostasis. Microphthalmia-associated transcription factor (MITF), a critical transcription factor in RPE cells, has two alternatively spliced isoforms: (+)MITF and (−)MITF. Previous work has sh...

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Detalles Bibliográficos
Autores principales: Hu, Xiaojuan, Li, Fang, He, Junhao, Yang, Juan, Jiang, Ye, Jiang, Mingyuan, Wei, Dandan, Chang, Lifu, Hejtmancik, J. Fielding, Hou, Ling, Ma, Xiaoyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Biochemistry and Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606808/
https://www.ncbi.nlm.nih.gov/pubmed/34787639
http://dx.doi.org/10.1167/iovs.62.14.18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606808/
https://www.ncbi.nlm.nih.gov/pubmed/34787639
http://dx.doi.org/10.1167/iovs.62.14.18

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