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LncRNA NEAT1 Recruits SFPQ to Regulate MITF Splicing and Control RPE Cell Proliferation
PURPOSE: Retinal pigment epithelium (RPE) cell proliferation is precisely regulated to maintain retinal homoeostasis. Microphthalmia-associated transcription factor (MITF), a critical transcription factor in RPE cells, has two alternatively spliced isoforms: (+)MITF and (−)MITF. Previous work has sh...
Autores principales: | Hu, Xiaojuan, Li, Fang, He, Junhao, Yang, Juan, Jiang, Ye, Jiang, Mingyuan, Wei, Dandan, Chang, Lifu, Hejtmancik, J. Fielding, Hou, Ling, Ma, Xiaoyin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606808/ https://www.ncbi.nlm.nih.gov/pubmed/34787639 http://dx.doi.org/10.1167/iovs.62.14.18 |
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