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Bulk Gene Expression Deconvolution Reveals Infiltration of M2 Macrophages in Retinal Neovascularization

PURPOSE: This study interrogated the transcriptional features and immune cellular landscape of the retinae of rats subjected to oxygen-induced retinopathy (OIR). METHODS: Bulk RNA sequencing was performed with retinal RNA isolated from control and OIR rats. Gene set enrichment analysis (GSEA) was un...

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Detalles Bibliográficos
Autores principales: Wang, Jiang-Hui, Kumar, Satheesh, Liu, Guei-Sheung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606818/
https://www.ncbi.nlm.nih.gov/pubmed/34797904
http://dx.doi.org/10.1167/iovs.62.14.22