Optogenetic Inhibition of Na(v)1.8 Expressing Corneal Afferents Reduces Persistent Dry Eye Pain

PURPOSE: The aim of the present study was to investigate the contribution of Nav1.8 expressing corneal afferent neurons to the presence of ongoing pain in lacrimal gland excision (LGE)-induced dry eye. METHODS: The proton pump archaerhodopsin-3/eGFP (ArchT/eGFP) was conditionally expressed in cornea...

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Detalles Bibliográficos
Autores principales: Mecum, Neal E., Russell, Rachel, Lee, Jun, Sullivan, Cara, Meng, Ian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Cornea
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606841/
https://www.ncbi.nlm.nih.gov/pubmed/34787642
http://dx.doi.org/10.1167/iovs.62.14.15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606841/
https://www.ncbi.nlm.nih.gov/pubmed/34787642
http://dx.doi.org/10.1167/iovs.62.14.15

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