Cargando…
Phosphorylation of Lamin A/C at serine 22 modulates Na(v)1.5 function
Variants in the LMNA gene, which encodes for Lamin A/C, are associated with cardiac conduction disease (CCD). We previously reported that Lamin A/C variants p.R545H and p.A287Lfs*193, which were identified in CCD patients, decreased peak I (Na) in HEK‐293 cells expressing Na(v)1.5. Decreased peak I...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606869/ https://www.ncbi.nlm.nih.gov/pubmed/34806324 http://dx.doi.org/10.14814/phy2.15121 |