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Strategies for induction of HIV‐1 envelope‐reactive broadly neutralizing antibodies

INTRODUCTION: A primary focus of HIV‐1 vaccine development is the activation of B cell receptors for naïve or precursor broadly neutralizing antibodies (bnAbs), followed by expansion and maturation of bnAb B cell lineage intermediates leading to highly affinity‐matured bnAbs. HIV‐1 envelope (Env) en...

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Detalles Bibliográficos
Autores principales: Williams, Wilton B., Wiehe, Kevin, Saunders, Kevin O., Haynes, Barton F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606870/
https://www.ncbi.nlm.nih.gov/pubmed/34806332
http://dx.doi.org/10.1002/jia2.25831