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Development of allogeneic HSC-engineered iNKT cells for off-the-shelf cancer immunotherapy

Cell-based immunotherapy has become the new-generation cancer medicine, and “off-the-shelf” cell products that can be manufactured at large scale and distributed readily to treat patients are necessary. Invariant natural killer T (iNKT) cells are ideal cell carriers for developing allogeneic cell th...

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Detalles Bibliográficos
Autores principales: Li, Yan-Ruide, Zhou, Yang, Kim, Yu Jeong, Zhu, Yanni, Ma, Feiyang, Yu, Jiaji, Wang, Yu-Chen, Chen, Xianhui, Li, Zhe, Zeng, Samuel, Wang, Xi, Lee, Derek, Ku, Josh, Tsao, Tasha, Hardoy, Christian, Huang, Jie, Cheng, Donghui, Montel-Hagen, Amélie, Seet, Christopher S., Crooks, Gay M., Larson, Sarah M., Sasine, Joshua P., Wang, Xiaoyan, Pellegrini, Matteo, Ribas, Antoni, Kohn, Donald B., Witte, Owen, Wang, Pin, Yang, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607011/
https://www.ncbi.nlm.nih.gov/pubmed/34841295
http://dx.doi.org/10.1016/j.xcrm.2021.100449