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CD19嵌合抗原受体T细胞靶向B细胞肿瘤细胞株过程中糖皮质激素对其扩增影响的体外研究

OBJECTIVE: To evaluate the effects of glucocorticoids (dexamethasone and methylprednisolone) on the proliferation of CD19 Chimeric antigen receptor (CAR) modified T cells in vitro. METHODS: Peripheral blood mononuclear cells from healthy volunteers were collected as T cells. CD19 CAR-T cells were pr...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial office of Chinese Journal of Hematology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607036/
https://www.ncbi.nlm.nih.gov/pubmed/34753229
http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2021.09.006