Inhibition of microRNA-494-3p activates Wnt signaling and reduces proinflammatory macrophage polarization in atherosclerosis

We have previously shown that treatment with third-generation antisense oligonucleotides against miR-494-3p (3GA-494) reduces atherosclerotic plaque progression and stabilizes lesions, both in early and established plaques, with reduced macrophage content in established plaques. Within the plaque, d...

Descripción completa

Detalles Bibliográficos
Autores principales: van Ingen, Eva, Foks, Amanda C., Woudenberg, Tamar, van der Bent, M. Leontien, de Jong, Alwin, Hohensinner, Philipp J., Wojta, Johann, Bot, Ilze, Quax, Paul.H.A., Nossent, Anne Yaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607137/
https://www.ncbi.nlm.nih.gov/pubmed/34853722
http://dx.doi.org/10.1016/j.omtn.2021.10.027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607137/
https://www.ncbi.nlm.nih.gov/pubmed/34853722
http://dx.doi.org/10.1016/j.omtn.2021.10.027

Ejemplares similares