Hepatocyte-derived exosomal miR-27a activateshepatic stellate cells through the inhibitionof PINK1-mediated mitophagy in MAFLD

The role of exosome-mediated mitophagy in the crosstalk between hepatocytes (HCs) and hepatic stellate cells (HSCs) in metabolic-associated fatty liver disease (MAFLD) remains unknown. Serum exosomal miR-27a levels were markedly increased and positively correlated with liver fibrosis in MAFLD patien...

Descripción completa

Detalles Bibliográficos
Autores principales: Luo, Xin, Xu, Zi-Xin, Wu, Jun-Cheng, Luo, Sheng-Zheng, Xu, Ming-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607138/
https://www.ncbi.nlm.nih.gov/pubmed/34853724
http://dx.doi.org/10.1016/j.omtn.2021.10.022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607138/
https://www.ncbi.nlm.nih.gov/pubmed/34853724
http://dx.doi.org/10.1016/j.omtn.2021.10.022

Ejemplares similares