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Discovery of a novel potentially transforming somatic mutation in CSF2RB gene in breast cancer

The colony stimulating factor 2 receptor subunit beta (CSF2RB) is the common signaling subunit of the cytokine receptors for IL‐3, IL‐5, and GM‐CSF. Several studies have shown that spontaneous and random mutants of CSF2RB can lead to ligand independence in vitro. To date, no report(s) have been show...

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Detalles Bibliográficos
Autores principales: Rashid, Mamoon, Ali, Rizwan, Almuzzaini, Bader, Song, Hao, AlHallaj, Alshaimaa, Abdulkarim, Al Abdulrahman, Mohamed Baz, Omar, Al Zahrani, Hajar, Mustafa Sabeena, Muhammed, Alharbi, Wardah, Hussein, Mohamed, Boudjelal, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607246/
https://www.ncbi.nlm.nih.gov/pubmed/34729943
http://dx.doi.org/10.1002/cam4.4106