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Tracer kinetic assessment of blood–brain barrier leakage and blood volume in cerebral small vessel disease: Associations with disease burden and vascular risk factors

Subtle blood–brain barrier (BBB) permeability increases have been shown in small vessel disease (SVD) using various analysis methods. Following recent consensus recommendations, we used Patlak tracer kinetic analysis, considered optimal in low permeability states, to quantify permeability-surface ar...

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Detalles Bibliográficos
Autores principales: Stringer, Michael S., Heye, Anna K., Armitage, Paul A., Chappell, Francesca, Valdés Hernández, Maria del C., Makin, Stephen D.J., Sakka, Eleni, Thrippleton, Michael J., Wardlaw, Joanna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607271/
https://www.ncbi.nlm.nih.gov/pubmed/34911189
http://dx.doi.org/10.1016/j.nicl.2021.102883