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Tracer kinetic assessment of blood–brain barrier leakage and blood volume in cerebral small vessel disease: Associations with disease burden and vascular risk factors
Subtle blood–brain barrier (BBB) permeability increases have been shown in small vessel disease (SVD) using various analysis methods. Following recent consensus recommendations, we used Patlak tracer kinetic analysis, considered optimal in low permeability states, to quantify permeability-surface ar...
Autores principales: | Stringer, Michael S., Heye, Anna K., Armitage, Paul A., Chappell, Francesca, Valdés Hernández, Maria del C., Makin, Stephen D.J., Sakka, Eleni, Thrippleton, Michael J., Wardlaw, Joanna M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607271/ https://www.ncbi.nlm.nih.gov/pubmed/34911189 http://dx.doi.org/10.1016/j.nicl.2021.102883 |
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