Curcumin derivative 1, 2-bis [(3E, 5E)-3, 5-bis [(2-chlorophenyl) methylene]-4-oxo-1-piperidyl] ethane-1, 2-dione (ST03) induces mitochondria mediated apoptosis in ovarian cancer cells and inhibits tumor progression in EAC mouse model

Curcumin is known for its anticancer properties, but its clinical application is limited due to its poor bioavailability and chemical stability. In this study we report the curcumin derivative, ST03 (1,2-bis[(3E,5E)-3,5-bis[(2-chlorophenyl)methylene]-4-oxo-1-piperidyl]ethane-1,2-dione) exhibits ∼ 14...

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Detalles Bibliográficos
Autores principales: Koroth, Jinsha, Mahadeva, Raghunandan, Ravindran, Febina, Parashar, Tanvi R, Teja, Vinay, Karki, Subhas S, Choudhary, Bibha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607274/
https://www.ncbi.nlm.nih.gov/pubmed/34801859
http://dx.doi.org/10.1016/j.tranon.2021.101280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607274/
https://www.ncbi.nlm.nih.gov/pubmed/34801859
http://dx.doi.org/10.1016/j.tranon.2021.101280

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