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KMT2D deficiency disturbs the proliferation and cell cycle activity of dental epithelial cell line (LS8) partially via Wnt signaling

Lysine methyltransferase 2D (KMT2D), as one of the key histone methyltransferases responsible for histone 3 lysine 4 methylation (H3K4me), has been proved to be the main pathogenic gene of Kabuki syndrome disease. Kabuki patients with KMT2D mutation frequently present various dental abnormalities, i...

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Detalles Bibliográficos
Autores principales: Pang, Liping, Tian, Hua, Gao, Xuejun, Wang, Weiping, Wang, Xiaoyan, Zhang, Zhichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607332/
https://www.ncbi.nlm.nih.gov/pubmed/34724040
http://dx.doi.org/10.1042/BSR20211148