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Interplay between SMAD2 and STAT5A is a critical determinant of IL-17A/IL-17F differential expression

Interleukins (IL)-17A and F are critical cytokines in anti-microbial immunity but also contribute to auto-immune pathologies. Recent evidence suggests that they may be differentially produced by T-helper (Th) cells, but the underlying mechanisms remain unknown. To address this question, we built a r...

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Detalles Bibliográficos
Autores principales: Corral-Jara, Karla Fabiola, Chauvin, Camille, Abou-Jaoudé, Wassim, Grandclaudon, Maximilien, Naldi, Aurélien, Soumelis, Vassili, Thieffry, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607379/
https://www.ncbi.nlm.nih.gov/pubmed/35006414
http://dx.doi.org/10.1186/s43556-021-00034-3