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Interplay between SMAD2 and STAT5A is a critical determinant of IL-17A/IL-17F differential expression
Interleukins (IL)-17A and F are critical cytokines in anti-microbial immunity but also contribute to auto-immune pathologies. Recent evidence suggests that they may be differentially produced by T-helper (Th) cells, but the underlying mechanisms remain unknown. To address this question, we built a r...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607379/ https://www.ncbi.nlm.nih.gov/pubmed/35006414 http://dx.doi.org/10.1186/s43556-021-00034-3 |