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α-Linolenic acid induces clearance of Tau seeds via Actin-remodeling in Microglia

Alzheimer’s disease (AD) is known by characteristic features, extracellular burden of amyloid-β and intracellular neuronal Tau. Microglia, the innate immune cell of the brain has the ability to clear the burden of accumulated proteins via phagocytosis. But the excessive proinflammatory cytokine prod...

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Detalles Bibliográficos
Autores principales: Desale, Smita Eknath, Chinnathambi, Subashchandrabose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607384/
https://www.ncbi.nlm.nih.gov/pubmed/35006402
http://dx.doi.org/10.1186/s43556-021-00028-1