Cargando…
α-Linolenic acid induces clearance of Tau seeds via Actin-remodeling in Microglia
Alzheimer’s disease (AD) is known by characteristic features, extracellular burden of amyloid-β and intracellular neuronal Tau. Microglia, the innate immune cell of the brain has the ability to clear the burden of accumulated proteins via phagocytosis. But the excessive proinflammatory cytokine prod...
Autores principales: | Desale, Smita Eknath, Chinnathambi, Subashchandrabose |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607384/ https://www.ncbi.nlm.nih.gov/pubmed/35006402 http://dx.doi.org/10.1186/s43556-021-00028-1 |
Ejemplares similares
-
α– Linolenic acid modulates phagocytosis and endosomal pathways of extracellular Tau in microglia
por: Desale, Smita Eknath, et al.
Publicado: (2021) -
Phosphoinositides signaling modulates microglial actin remodeling and phagocytosis in Alzheimer’s disease
por: Desale, Smita Eknath, et al.
Publicado: (2021) -
Role of dietary fatty acids in microglial polarization in Alzheimer’s disease
por: Desale, Smita Eknath, et al.
Publicado: (2020) -
Phagocytosis of full-length Tau oligomers by Actin-remodeling of activated microglia
por: Das, Rashmi, et al.
Publicado: (2020) -
G-protein coupled receptor, PI3K and Rho signaling pathways regulate the cascades of Tau and amyloid-β in Alzheimer’s disease
por: Desale, Smita Eknath, et al.
Publicado: (2021)