GEF-independent Ran activation shifts a fraction of the protein to the cytoplasm and promotes cell proliferation

Ran (Ras-related nuclear protein) plays several important roles in nucleo-cytoplasmic transport, mitotic spindle formation, nuclear envelope/nuclear pore complex assembly, and other functions in the cytoplasm, as well as in cellular transformation when switched on. Unlike other members of the GTPase...

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Detalles Bibliográficos
Autores principales: Zhou, Jinhan, Tan, Yuping, Zhang, Yuqing, Tong, Aiping, Shen, Xiaofei, Sun, Xiaodong, Jia, Da, Sun, Qingxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607414/
https://www.ncbi.nlm.nih.gov/pubmed/35006421
http://dx.doi.org/10.1186/s43556-020-00011-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607414/
https://www.ncbi.nlm.nih.gov/pubmed/35006421
http://dx.doi.org/10.1186/s43556-020-00011-2

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