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GEF-independent Ran activation shifts a fraction of the protein to the cytoplasm and promotes cell proliferation
Ran (Ras-related nuclear protein) plays several important roles in nucleo-cytoplasmic transport, mitotic spindle formation, nuclear envelope/nuclear pore complex assembly, and other functions in the cytoplasm, as well as in cellular transformation when switched on. Unlike other members of the GTPase...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Singapore
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607414/ https://www.ncbi.nlm.nih.gov/pubmed/35006421 http://dx.doi.org/10.1186/s43556-020-00011-2 |