miR-221/222 sponge abrogates tamoxifen resistance in ER-positive breast cancer cells through restoring the expression of ERα

Tamoxifen resistance (TamR) prevents ER-positive breast cancer patients from benefitting from endocrine therapy, and miR-221 or miR-222 plays vital roles in inducing TamR. In this study, we designed synthetic sponges to reverse TamR by targeting these two miRs. First, we established a tamoxifen resi...

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Detalles Bibliográficos
Autores principales: Ouyang, Yan Xiu, Feng, Jun, Wang, Zun, Zhang, Guo Jun, Chen, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607419/
https://www.ncbi.nlm.nih.gov/pubmed/35006452
http://dx.doi.org/10.1186/s43556-021-00045-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607419/
https://www.ncbi.nlm.nih.gov/pubmed/35006452
http://dx.doi.org/10.1186/s43556-021-00045-0

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