Random-PE: an efficient integration of random sequences into mammalian genome by prime editing

Prime editing (PE) enables efficiently targeted introduction of multiple types of small-sized genetic change without requiring double-strand breaks or donor templates. Here we designed a simple strategy to introduce random DNA sequences into targeted genomic loci by prime editing, which we named ran...

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Detalles Bibliográficos
Autores principales: Jiao, Yaoge, Zhou, Lifang, Tao, Rui, Wang, Yanhong, Hu, Yun, Jiang, Lurong, Li, Li, Yao, Shaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607425/
https://www.ncbi.nlm.nih.gov/pubmed/35006470
http://dx.doi.org/10.1186/s43556-021-00057-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607425/
https://www.ncbi.nlm.nih.gov/pubmed/35006470
http://dx.doi.org/10.1186/s43556-021-00057-w

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