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TMPRSS4 promotes cancer stem–like properties in prostate cancer cells through upregulation of SOX2 by SLUG and TWIST1

BACKGROUND: Transmembrane serine protease 4 (TMPRSS4) is a cell surface–anchored serine protease. Elevated expression of TMPRSS4 correlates with poor prognosis in colorectal cancer, gastric cancer, prostate cancer, non–small cell lung cancer, and other cancers. Previously, we demonstrated that TMPRS...

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Detalles Bibliográficos
Autores principales: Lee, Yunhee, Yoon, Junghwa, Ko, Dongjoon, Yu, Minyeong, Lee, Soojin, Kim, Semi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607621/
https://www.ncbi.nlm.nih.gov/pubmed/34809669
http://dx.doi.org/10.1186/s13046-021-02147-7