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PA and OA induce abnormal glucose metabolism by inhibiting KLF15 in adipocytes

BACKGROUND: Obesity-induced elevated serum free fatty acids (FFAs) levels result in the occurrence of type 2 diabetes mellitus (T2DM). However, the molecular mechanism remains largely enigmatic. This study was to explore the effect and mechanism of KLF15 on FFAs-induced abnormal glucose metabolism....

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Detalles Bibliográficos
Autores principales: Wang, Cuizhe, Chu, Xiaolong, Deng, Yuchun, Wang, Jingzhou, Qiu, Tongtong, Zhu, Jiaojiao, Yang, Xin, Pan, Chongge, Xiong, Jianyu, Xie, Jianxin, Chang, Yongsheng, Zhang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607635/
https://www.ncbi.nlm.nih.gov/pubmed/34802421
http://dx.doi.org/10.1186/s12986-021-00628-2