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Transplantation of human embryonic stem cells alleviates motor dysfunction in AAV2-Htt171-82Q transfected rat model of Huntington’s disease

BACKGROUND: Human embryonic stem cells (hESCs) transplantation had shown to provide a potential source of cells in neurodegenerative disease studies and lead to behavioral recovery in lentivirus transfected or, toxin-induced Huntington's disease (HD) rodent model. Here, we aimed to observe if t...

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Detalles Bibliográficos
Autores principales: Islam, Jaisan, So, Kyoung Ha, KC, Elina, Moon, Hyeong Cheol, Kim, Aryun, Hyun, Sang Hwan, Kim, Soochong, Park, Young Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607638/
https://www.ncbi.nlm.nih.gov/pubmed/34809707
http://dx.doi.org/10.1186/s13287-021-02653-7