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Prodrug polymeric micelles integrating cancer-associated fibroblasts deactivation and synergistic chemotherapy for gastric cancer

BACKGROUND: The prognosis of patients with advanced gastric cancer (GC) remains unsatisfactory owing to distant metastasis and resistance to concurrent systemic therapy. Cancer-associated fibroblasts (CAFs), as essential participators in the tumor microenvironment (TME), play a vital role in tumor p...

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Detalles Bibliográficos
Autores principales: Zheng, Sheng, Wang, Jiafeng, Ding, Ning, Chen, Wenwen, Chen, Hongda, Xue, Meng, Chen, Fei, Ni, Jiaojiao, Wang, Zhuo, Lin, Zhenghua, Jiang, Haiping, Liu, Xiangrui, Wang, Liangjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607732/
https://www.ncbi.nlm.nih.gov/pubmed/34802453
http://dx.doi.org/10.1186/s12951-021-01127-5