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Prodrug polymeric micelles integrating cancer-associated fibroblasts deactivation and synergistic chemotherapy for gastric cancer
BACKGROUND: The prognosis of patients with advanced gastric cancer (GC) remains unsatisfactory owing to distant metastasis and resistance to concurrent systemic therapy. Cancer-associated fibroblasts (CAFs), as essential participators in the tumor microenvironment (TME), play a vital role in tumor p...
Autores principales: | Zheng, Sheng, Wang, Jiafeng, Ding, Ning, Chen, Wenwen, Chen, Hongda, Xue, Meng, Chen, Fei, Ni, Jiaojiao, Wang, Zhuo, Lin, Zhenghua, Jiang, Haiping, Liu, Xiangrui, Wang, Liangjing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607732/ https://www.ncbi.nlm.nih.gov/pubmed/34802453 http://dx.doi.org/10.1186/s12951-021-01127-5 |
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