Sox6 expression distinguishes dorsally and ventrally biased dopamine neurons in the substantia nigra with distinctive properties and embryonic origins

Dopamine (DA) neurons in the ventral tier of the substantia nigra pars compacta (SNc) degenerate prominently in Parkinson’s disease, while those in the dorsal tier are relatively spared. Defining the molecular, functional, and developmental characteristics of each SNc tier is crucial to understand t...

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Detalles Bibliográficos
Autores principales: Luppi, Milagros Pereira, Azcorra, Maite, Caronia-Brown, Giuliana, Poulin, Jean-Francois, Gaertner, Zachary, Gatica, Serafin, Moreno-Ramos, Oscar Andrés, Nouri, Navid, Dubois, Marilyn, Ma, Yongchao C., Ramakrishnan, Charu, Fenno, Lief, Kim, Yoon Seok, Deisseroth, Karl, Cicchetti, Francesca, Dombeck, Daniel A., Awatramani, Rajeshwar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607753/
https://www.ncbi.nlm.nih.gov/pubmed/34758317
http://dx.doi.org/10.1016/j.celrep.2021.109975

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607753/
https://www.ncbi.nlm.nih.gov/pubmed/34758317
http://dx.doi.org/10.1016/j.celrep.2021.109975

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