Tumour‐derived small extracellular vesicles suppress CD8+ T cell immune function by inhibiting SLC6A8‐mediated creatine import in NPM1‐mutated acute myeloid leukaemia

Acute myeloid leukaemia (AML) carrying nucleophosmin (NPM1) mutations has been defined as a distinct entity of acute leukaemia. Despite remarkable improvements in diagnosis and treatment, the long‐term outcomes for this entity remain unsatisfactory. Emerging evidence suggests that leukaemia, similar...

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Detalles Bibliográficos
Autores principales: Peng, Meixi, Ren, Jun, Jing, Yipei, Jiang, Xueke, Xiao, Qiaoling, Huang, Junpeng, Tao, Yonghong, Lei, Li, Wang, Xin, Yang, Zailin, Yang, Zesong, Zhan, Qian, Lin, Can, Jin, Guoxiang, Zhang, Xian, Zhang, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607980/
https://www.ncbi.nlm.nih.gov/pubmed/34807526
http://dx.doi.org/10.1002/jev2.12168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607980/
https://www.ncbi.nlm.nih.gov/pubmed/34807526
http://dx.doi.org/10.1002/jev2.12168

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