Cargando…
Tumour‐derived small extracellular vesicles suppress CD8+ T cell immune function by inhibiting SLC6A8‐mediated creatine import in NPM1‐mutated acute myeloid leukaemia
Acute myeloid leukaemia (AML) carrying nucleophosmin (NPM1) mutations has been defined as a distinct entity of acute leukaemia. Despite remarkable improvements in diagnosis and treatment, the long‐term outcomes for this entity remain unsatisfactory. Emerging evidence suggests that leukaemia, similar...
Autores principales: | Peng, Meixi, Ren, Jun, Jing, Yipei, Jiang, Xueke, Xiao, Qiaoling, Huang, Junpeng, Tao, Yonghong, Lei, Li, Wang, Xin, Yang, Zailin, Yang, Zesong, Zhan, Qian, Lin, Can, Jin, Guoxiang, Zhang, Xian, Zhang, Ling |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607980/ https://www.ncbi.nlm.nih.gov/pubmed/34807526 http://dx.doi.org/10.1002/jev2.12168 |
Ejemplares similares
-
Mutant NPM1-regulated lncRNA HOTAIRM1 promotes leukemia cell autophagy and proliferation by targeting EGR1 and ULK3
por: Jing, Yipei, et al.
Publicado: (2021) -
Targeted activation of GPER enhances the efficacy of venetoclax by boosting leukemic pyroptosis and CD8+ T cell immune function in acute myeloid leukemia
por: Ren, Jun, et al.
Publicado: (2022) -
Cytoplasmic Expression of TP53INP2 Modulated by Demethylase FTO and Mutant NPM1 Promotes Autophagy in Leukemia Cells
por: Huang, Junpeng, et al.
Publicado: (2023) -
Mutant NPM1-Regulated FTO-Mediated m(6)A Demethylation Promotes Leukemic Cell Survival via PDGFRB/ERK Signaling Axis
por: Xiao, Qiaoling, et al.
Publicado: (2022) -
Circulating plasma exosomal long non-coding RNAs LINC00265, LINC00467, UCA1, and SNHG1 as biomarkers for diagnosis and treatment monitoring of acute myeloid leukemia
por: Xiao, Qiaoling, et al.
Publicado: (2022)