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Endothelial METTL3 (Methyltransferase-Like 3) Inhibits Fibrinolysis by Promoting PAI-1 (Plasminogen Activator Inhibitor-1) Expression Through Enhancing Jun Proto-Oncogene N6-Methyladenosine Modification

OBJECTIVE: METTL3 (methyltransferase-like protein 3)-mediated N(6)-methyladenosine modification is the most abundant RNA modification on eukaryote mRNAs and plays a crucial role in diverse physiological and pathological processes. However, whether N(6)-methyladenosine modification has function in th...

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Detalles Bibliográficos
Autores principales: Bai, Qin, Lu, Yao, Chen, Yanhua, Zhang, Han, Zhang, Weiwei, Wu, Huang, Wen, Aiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608005/
https://www.ncbi.nlm.nih.gov/pubmed/34645279
http://dx.doi.org/10.1161/ATVBAHA.121.316414