The ASCIZ-DYNLL1 Axis Is Essential for TLR4-Mediated Antibody Responses and NF-κB Pathway Activation

Toll-like receptors (TLRs) and interleukin-1 (IL-1) receptors regulate immune and inflammatory responses by activating the NF-κB pathway. Here, we report that B-cell‐specific loss of dynein light chain 1 (DYNLL1, LC8) or its designated transcription factor ASCIZ (ATMIN) leads to severely reduced in...

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Detalles Bibliográficos
Autores principales: Liu, Rui, King, Ashleigh, Tarlinton, David, Heierhorst, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608018/
https://www.ncbi.nlm.nih.gov/pubmed/34543116
http://dx.doi.org/10.1128/MCB.00251-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608018/
https://www.ncbi.nlm.nih.gov/pubmed/34543116
http://dx.doi.org/10.1128/MCB.00251-21

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