Germline Testing Data Validate Inferences of Mutational Status for Variants Detected From Tumor-Only Sequencing

Pathogenic germline variants (PGVs) in cancer susceptibility genes are usually identified through germline testing of DNA from blood or saliva: their detection can affect treatment options and potential risk-reduction strategies for patient relatives. PGV can also be identified in tumor sequencing a...

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Detalles Bibliográficos
Autores principales: Jalloul, Nahed, Gomy, Israel, Stokes, Samantha, Gusev, Alexander, Johnson, Bruce E., Lindeman, Neal I., Macconaill, Laura, Ganesan, Shridar, Garber, Judy E., Khiabanian, Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2021
Materias:
ORIGINAL REPORTS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608266/
https://www.ncbi.nlm.nih.gov/pubmed/34820595
http://dx.doi.org/10.1200/PO.21.00279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608266/
https://www.ncbi.nlm.nih.gov/pubmed/34820595
http://dx.doi.org/10.1200/PO.21.00279

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