Activated heme synthesis regulates glycolysis and oxidative metabolism in breast and ovarian cancer cells

Heme is an essential cofactor for enzymes of the electron transport chain (ETC) and ATP synthesis in mitochondrial oxidative phosphorylation (OXPHOS). Heme also binds to and destabilizes Bach1, a transcription regulator that controls expression of several groups of genes important for glycolysis, ET...

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Detalles Bibliográficos
Autores principales: Kaur, Pritpal, Nagar, Shreya, Bhagwat, Madhura, Uddin, Mohammad, Zhu, Yan, Vancurova, Ivana, Vancura, Ales
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608300/
https://www.ncbi.nlm.nih.gov/pubmed/34807950
http://dx.doi.org/10.1371/journal.pone.0260400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608300/
https://www.ncbi.nlm.nih.gov/pubmed/34807950
http://dx.doi.org/10.1371/journal.pone.0260400

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