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Activated heme synthesis regulates glycolysis and oxidative metabolism in breast and ovarian cancer cells
Heme is an essential cofactor for enzymes of the electron transport chain (ETC) and ATP synthesis in mitochondrial oxidative phosphorylation (OXPHOS). Heme also binds to and destabilizes Bach1, a transcription regulator that controls expression of several groups of genes important for glycolysis, ET...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608300/ https://www.ncbi.nlm.nih.gov/pubmed/34807950 http://dx.doi.org/10.1371/journal.pone.0260400 |