ΔFBA—Predicting metabolic flux alterations using genome-scale metabolic models and differential transcriptomic data

Genome-scale metabolic models (GEMs) provide a powerful framework for simulating the entire set of biochemical reactions in a cell using a constraint-based modeling strategy called flux balance analysis (FBA). FBA relies on an assumed metabolic objective for generating metabolic fluxes using GEMs. B...

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Detalles Bibliográficos
Autores principales: Ravi, Sudharshan, Gunawan, Rudiyanto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608322/
https://www.ncbi.nlm.nih.gov/pubmed/34758020
http://dx.doi.org/10.1371/journal.pcbi.1009589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608322/
https://www.ncbi.nlm.nih.gov/pubmed/34758020
http://dx.doi.org/10.1371/journal.pcbi.1009589

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