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DNA bridges: A novel platform for single-molecule sequencing and other DNA-protein interaction applications

DNA molecular combing is a technique that stretches thousands of long individual DNA molecules (up to 10 Mbp) into a parallel configuration on surface. It has previously been proposed to sequence these molecules by synthesis. However, this approach poses two critical challenges: 1-Combed DNA molecul...

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Detalles Bibliográficos
Autores principales: Righini, Maurizio, Costa, Justin, Zhou, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608331/
https://www.ncbi.nlm.nih.gov/pubmed/34807931
http://dx.doi.org/10.1371/journal.pone.0260428