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Cyclophosphamide Attenuates Fibrosis in Lupus Nephritis by Regulating Mesangial Cell Cycle Progression

OBJECTIVES: Most patients with systemic lupus erythematosus (SLE) develop lupus nephritis (LN) with severe kidney manifestations. Renal fibrosis can be primarily attributed to overproliferation of mesangial cells (MCs), which are subject to drug treatment. Nevertheless, the detailed mechanisms remai...

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Detalles Bibliográficos
Autores principales: Ma, Yuehong, Fang, Ling, Zhang, Rui, Zhao, Peng, Li, Yafeng, Li, Rongshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608492/
https://www.ncbi.nlm.nih.gov/pubmed/34820026
http://dx.doi.org/10.1155/2021/3803601