Cargando…
Cyclophosphamide Attenuates Fibrosis in Lupus Nephritis by Regulating Mesangial Cell Cycle Progression
OBJECTIVES: Most patients with systemic lupus erythematosus (SLE) develop lupus nephritis (LN) with severe kidney manifestations. Renal fibrosis can be primarily attributed to overproliferation of mesangial cells (MCs), which are subject to drug treatment. Nevertheless, the detailed mechanisms remai...
Autores principales: | Ma, Yuehong, Fang, Ling, Zhang, Rui, Zhao, Peng, Li, Yafeng, Li, Rongshan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608492/ https://www.ncbi.nlm.nih.gov/pubmed/34820026 http://dx.doi.org/10.1155/2021/3803601 |
Ejemplares similares
-
Mesangial cell: A hub in lupus nephritis
por: Liu, Mengdi, et al.
Publicado: (2022) -
Mycophenolate versus Cyclophosphamide for Lupus Nephritis
por: Sahay, M., et al.
Publicado: (2018) -
Revisited Cyclophosphamide in the Treatment of Lupus Nephritis
por: Quan, Xiao-ying, et al.
Publicado: (2022) -
Trifluoperazine induces apoptosis through the upregulation of Bax/Bcl-2 and downregulated phosphorylation of AKT in mesangial cells and improves renal function in lupus nephritis mice
por: Wang, Baodong, et al.
Publicado: (2018) -
Effect of immunosuppression on the human mesangial cell cycle
por: ZHOU, XIAOSHUANG, et al.
Publicado: (2015)