ULK1 Suppresses Osteoclast Differentiation and Bone Resorption via Inhibiting Syk-JNK through DOK3

Bone resorption diseases, including osteoporosis, are usually caused by excessive osteoclastogenesis. Unc-51-like autophagy activating kinase 1 (ULK1), a mammalian serine/threonine kinase, may participate in the regulation of bone homeostasis and osteolytic metastasis. In this study, ULK1 expression...

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Detalles Bibliográficos
Autores principales: Zhang, Yufeng, Zhang, Sheng, Wang, Yi, Yang, Zhiqiang, Chen, Zhe, Wen, Nengqiao, Yang, Min, Huang, Zan, Xie, Yuanlong, Cai, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608530/
https://www.ncbi.nlm.nih.gov/pubmed/34820053
http://dx.doi.org/10.1155/2021/2896674

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608530/
https://www.ncbi.nlm.nih.gov/pubmed/34820053
http://dx.doi.org/10.1155/2021/2896674

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