Cargando…
ULK1 Suppresses Osteoclast Differentiation and Bone Resorption via Inhibiting Syk-JNK through DOK3
Bone resorption diseases, including osteoporosis, are usually caused by excessive osteoclastogenesis. Unc-51-like autophagy activating kinase 1 (ULK1), a mammalian serine/threonine kinase, may participate in the regulation of bone homeostasis and osteolytic metastasis. In this study, ULK1 expression...
Autores principales: | Zhang, Yufeng, Zhang, Sheng, Wang, Yi, Yang, Zhiqiang, Chen, Zhe, Wen, Nengqiao, Yang, Min, Huang, Zan, Xie, Yuanlong, Cai, Lin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608530/ https://www.ncbi.nlm.nih.gov/pubmed/34820053 http://dx.doi.org/10.1155/2021/2896674 |
Ejemplares similares
-
BHLHE40 promotes osteoclastogenesis and abnormal bone resorption via c-Fos/NFATc1
por: Zhang, Yufeng, et al.
Publicado: (2022) -
Role of Dok-1 and Dok-2 in Leukemia Suppression
por: Niki, Masaru, et al.
Publicado: (2004) -
Syk, c-Src, the αvβ3 integrin, and ITAM immunoreceptors, in concert, regulate osteoclastic bone resorption
por: Zou, Wei, et al.
Publicado: (2007) -
Role of Dok-1 and Dok-2 in Myeloid Homeostasis and Suppression of Leukemia
por: Yasuda, Tomoharu, et al.
Publicado: (2004) -
Osteoclasts secrete osteopontin into resorption lacunae during bone resorption
por: Luukkonen, Jani, et al.
Publicado: (2019)