Wild type, dEX3 and 2B survivin isoforms localize to the tumor cell plasma membrane, are secreted in exosomes, and interact with extracellular tubulin

The Inhibitor of Apoptosis Protein survivin (svn) is upregulated in nearly all types of cancer and represents a promising therapeutic target. Localization to specific subcellular compartments and interactions with various binding partners allow survivin to play diverse roles in apoptosis resistance...

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Detalles Bibliográficos
Autores principales: Figel, Sheila, Birkemeier, Meaghan, Dharma, Sanam Sahjram, Barone, Tara, Steinmetz, Emma, Ciesielski, Michael, Fenstermaker, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608592/
https://www.ncbi.nlm.nih.gov/pubmed/34849411
http://dx.doi.org/10.1016/j.bbrep.2021.101174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608592/
https://www.ncbi.nlm.nih.gov/pubmed/34849411
http://dx.doi.org/10.1016/j.bbrep.2021.101174

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