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Redox regulation of DUBs and its therapeutic implications in cancer

Reactive oxygen species (ROS) act as a double-edged sword in cancer, where low levels of ROS are beneficial but excessive accumulation leads to cancer progression. Elevated levels of ROS in cancer are counteracted by the antioxidant defense system. An imbalance between ROS generation and the antioxi...

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Detalles Bibliográficos
Autores principales: Tyagi, Apoorvi, Haq, Saba, Ramakrishna, Suresh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608616/
https://www.ncbi.nlm.nih.gov/pubmed/34814083
http://dx.doi.org/10.1016/j.redox.2021.102194