The histone chaperone FACT facilitates heterochromatin spreading by regulating histone turnover and H3K9 methylation states

Heterochromatin formation requires three distinct steps: nucleation, self-propagation (spreading) along the chromosome, and faithful maintenance after each replication cycle. Impeding any of those steps induces heterochromatin defects and improper gene expression. The essential histone chaperone FAC...

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Detalles Bibliográficos
Autores principales: Murawska, Magdalena, Greenstein, R.A., Schauer, Tamas, Olsen, Karl C.F., Ng, Henry, Ladurner, Andreas G., Al-Sady, Bassem, Braun, Sigurd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608617/
https://www.ncbi.nlm.nih.gov/pubmed/34731638
http://dx.doi.org/10.1016/j.celrep.2021.109944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8608617/
https://www.ncbi.nlm.nih.gov/pubmed/34731638
http://dx.doi.org/10.1016/j.celrep.2021.109944

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